Extended Data Fig. 4: Sequence alignment of the S proteins of seven human coronaviruses indicates seven conserved sequences in S2. | Nature Microbiology

Extended Data Fig. 4: Sequence alignment of the S proteins of seven human coronaviruses indicates seven conserved sequences in S2.

From: Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

Extended Data Fig. 4

100% Identical residues are denoted in red background. The blue line indicates fusion peptide. The 7 conserved sequences are labeled with black dotted lines. The S1/S2 and S2’ cleavage sites of SARS-CoV-2 are annotated above the site. The sequence alignment was conducted by ESPript54. The sequences used in the alignment are: SARS-CoV-2 (NCBI GenBank: MT121215.1), SARS-CoV (NCBI GenBank: ABF65836.1), MERS-CoV (NCBI GenBank: AKN11072.1), HCoV-229E (NCBI GenBank: NP_073551.1), HCoV-NL63 (NCBI GenBank: YP_003767.1), HCoV-OC43 (NCBI GenBank: YP_009555241.1), HCoV-HKU1 (NCBI GenBank: ABD75513.1).

Back to article page