Extended Data Fig. 2: Pseudovirus Neutralization Assay. | Nature Microbiology

Extended Data Fig. 2: Pseudovirus Neutralization Assay.

From: Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern

Extended Data Fig. 2

(a) Scheme (generated using Biorender) depicting the pseudovirus neutralization assay performed in BBV152 vaccinated and COVID-19 mild disease recovered individuals using pseudovirus expressing full-length spike protein of the ancestral SARS-CoV-2 and its variants; Alpha (B.1.1.7), Beta (B.1.351) and Delta (B.1.617.2). (b) Neutralization curves for plasma samples derived from the representative pre-pandemic healthy donors (n = 10), BBV152 vaccinated (n = 15) and COVID-19 recovered individuals (n = 15) corresponding to the ancestral SARS-CoV-2 and the VoCs spike pseudoviruses.

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