Fig. 3: Distribution and ancestral inference of phenotypic traits and pathways across Rickettsiales.
From: The evolutionary origin of host association in the Rickettsiales
a, Presence (full circle) and absence (empty circle) of genes or pathways in the seven Rickettsiales families (including Gamibacteraceae, Athabascaceae and Mitibacteraceae), the alphaproteobacterial outgroup as well as the last common ancestors of the classical, obligate host-associated Rickettsiales (LhRCA) and of all Rickettsiales (LRCA). Pathways are grouped into ‘secretion’ (yellow), ‘motility’ (blue), ‘biosynthesis and transport’ (orange) and ‘electron transport chain’ (green). In some cases, pathways are either partial (one or several genes missing) or are absent from some species, but present in others (half circle). Numbers inside the circles represent the number of complete pathways for the biosynthesis of amino acids. The Gln transporter could potentially also transport other polar amino acids such as Ser, Thr and Asn. b, Synteny of the Rickettsiales vir homologue (rvh) T4SS in classical (black) and environmental (red) Rickettsiales. Taxa are ordered according to the species tree in a. One representative per family except Athabascaceae and Mitibacteraceae with two representatives each. c, Schematic phylogenetic tree showing the common duplication of the virB4 gene in LRCA. See Supplementary Fig. 10 for the uncollapsed tree. P-T4SS, type IV secretion system of the P type; T1SS, type I secretion system; CONJ, conjugation system; T4P, type 4 pilus; Tad, tight adherence system.
