Fig. 4: Core genome characterization of Enterobacter spp. isolates.

The phylogenetic tree of 209 Enterobacter spp. genomes including 111 from BARNARDS and 98 from other studies12,13,15 is shown, using Roary (v.3.12.0)55 and FastTree (v.2.1.11)56. Isolates are coloured at the endpoint according to country and the outer ring abbreviation is labelled according to the sample source. STs for all isolates are shown in the text after the sample source. The additional two outer rings denote the presence of blaNDM and blaOXA-48-like genes. Clades containing isolates from the present study are highlighted in teal, green clades indicate Enterobacter spp. neonatal sepsis isolates from other studies and pink Enterobacter spp. rectal carriage from different studies. Major STs are labelled around the phylogeny. For site acronyms, see Methods.