Fig. 3: The murine gut microbiota can transform cholesterol to CholSulf.
From: Characterization of interactions of dietary cholesterol with the murine and human gut microbiome
a, Representative structure of coprostanol alkyne. Ion chromatograms depicting detection of coprostanol alkyne from caecal content, E. cop cultures, and ex vivo stool cultures. b, Representative structure of CholAlk-Sulf. Ion chromatograms depicting detection of CholAlk-Sulf in caecal content and ex vivo stool cultures. c, Bacterial cholesterol sulfotransferase candidates identified from metagenomic analysis were screened for CholSulf production. Species-specific cultures were treated with cholesterol. Ion chromatograms represent the detection of CholSulf (n = 2 biological replicates per species, representative traces shown here).
