Extended Data Fig. 3: Metabolome and host multi-omic profiles in COPD and controls. | Nature Microbiology

Extended Data Fig. 3: Metabolome and host multi-omic profiles in COPD and controls.

From: Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions

Extended Data Fig. 3

Association of differential a) metabolome modules, b) host transcriptome modules, c) sputum proteome features and d) serum proteome features with sputum neutrophil and eosinophil percentages. Significance was determined using two-sided Wilcoxon rank-sum test, adjusting for multiple comparisons. The X-axis and Y-axis denote minus log10 (FDR P-value) times directionality of correlation for neutrophil and eosinophil, respectively. The full ordination space is divided into colored area for associations with neutrophil only, eosinophil only, neutrophil and eosinophil, and neither (FDR < 0.1).

Back to article page