Extended Data Fig. 1: Phylogenetic analysis of nitrate reductases.

Analysis of the Nar, Nap, and Nas nitrate reductase families in human (a) gut and (b) oral microbes, using the NarG and NapA protein sequences of E. coli, and NasA of K. pneumoniae as templates. The sequences were searched in the assembled gene catalog from Pasolli et al. (2019)55. (c) Phylogenetic tree of NarG in gut microbes reveals that Veillonella is one of the few genera within the Firmicutes with a putative nitrate reductase. Genes with at least 45% amino acid similarity were used for analysis.