Fig. 1: sVNT and pVNT assay.
From: SARS-CoV-2 Omicron variant emerged under immune selection
a, A heat map of sVNT GMT50 of 20 serum panels derived from convalescent, vaccinated, boosted and hybrid individuals for immunity against 20 sarbecoviruses using multiplex sVNT. b, Illustration of the clade-1b (SARS-CoV-2, RaTG13 and GX-P5L) and clade-2 (RmYN02 and SL-ZC45) RBDs used in rabbit immunization. The receptor binding motif is highlighted in blue. The percentage of amino acid sequence identity to SARS-CoV-2 RBD is indicated. c,d, The NAb level of the hyperimmune rabbit sera to different sarbecoviruses were determined by 20-plex sVNT (c) and pVNT (d) of different sarbecovirus spike proteins indicated above the panels.
