Extended Data Fig. 10: The PPI reporter SURF can be used to image interaction between spike and NRP1. | Nature Microbiology

Extended Data Fig. 10: The PPI reporter SURF can be used to image interaction between spike and NRP1.

From: Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2

Extended Data Fig. 10

Spike (529-685aa) and NRP1 (273-429aa) are fused to each part of SURF. The SURF reporter was transiently co-transfected into HEK293T with mApple_T2A_H2B-mIFP. Green: SURF fluorescence. Red: mCherry fluorescence. Blue: mIFP fluorescence. Scale bar: 20 μm. The experiments were repeated for three times independently with similar results.

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