Fig. 5: ANME-1 viral genomes encode complex structures.
From: Evolutionary diversification of methanotrophic ANME-1 archaea and their expansive virome
a, Evolutionary division between head-tailed viruses targeting ANME-1 and haloarchaea revealed by global proteome-based phylogenetic analyses. ANME-1 viruses with complete circular genomes are highlighted in purple, those with unconfirmed completeness are in blue. b,c, Genome organization and gene content of the complete genomes representing two families of ANME-1 head-tailed viruses Ahpuchviridae (b) and Ekchuahviridae (c). Blue and purple shading represents forward and reverse strands, respectively. MCP, PolB and ThyX genes are highlighted in pink and red. d, Circular alignment of the two genomes of ekchuahviruses. Black arrowheads indicate the original contig start/end sites in each assembly. e, Gene content of the complete linear genome of a representative of the rod-shaped virus familyAhmunviridae. f, Gene synteny of three families of spindle-shaped viruses targeting ANME-1, where complete, circularized genomes of Itzamnaviridae were found to occur in two genome sizes, where Demiitzamnavirus representatives align with a section of the larger Pletoitzamnavirus genomes (illustrated on the top right). Different colours indicate 76 different protein groups. Grey shading denotes singletons. The scale bar and percent identity shading are indicated in the bottom right. g, Gene content of the complete linear genome of a representative of the spindle-shaped virus family Itzamnaviridae. Dashed red box in (f) and (g) highlights an example of a multigene cluster insertion. In (d) and (f), the structural arm denotes the genome fraction where all viral structural genes reside; the enzymatic arm denotes the fraction where there are no structural genes and only enzyme-encoding genes reside.
