Extended Data Fig. 4: Statistical analysis of links between biomarkers and pleocytosis during TI.
Selected biomarker data presented in Fig. 4 and Extended Data Fig. 3 were pooled based on the presence or absence of pleocytosis (WBC count greater than or less than 5/μl, respectively) in the CSF. These two groups were compared for IP-10 (a), MMP9 (b), neopterin (c), NfL (d), or the neurocognitive score QNPZ4 (e). The groups were compared using the two-sided Mann-Whitney test, with the p values indicated on each graph. A Bonferroni correction for multiple comparisons indicates a significant p value cutoff of 0.01. No corrections were made for the fact that multiple values were included for each participant.
