Extended Data Fig. 5: Detailed analysis of the interactions between FtsB and FtsL, FtsW and FtsL and FtsI and FtsL.
From: Cryo-EM structure of the bacterial divisome core complex and antibiotic target FtsWIQBL
a) Interaction sites between FtsB and FtsL, as also indicated in Fig. 2a. Residues of FtsL that also interact with FtsI are highlighted in blue. b) Analysis of the interaction sites between FtsL and FtsW in their transmembrane region. The coiled coil conformation of FtsL means that the interaction surface is not as extended as it would be if it were straighter and not in a coiled coil. c) Electrostatic analysis of the interactions between FtsI and FtsL shows that the interaction site in the coiled coil area is mainly hydrophobic/neutral.
