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Bacterial pathogenesis

Autophagy is part of the answer to tuberculosis

Nature Microbiology volume 8, pages 762–763 (2023)Cite this article

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Almost twenty years after it was first linked to control of Mycobacterium tuberculosis in macrophages, autophagy retakes centre stage, as shown in murine models and human cells.

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Fig. 1: Canonical and non-canonical ATG-dependent processes contribute to control of M. tuberculosis.

References

  1. Gutierrez, M. G. et al. Cell 119, 753–766 (2004).

    Article  CAS  PubMed  Google Scholar 

  2. Watson, R. O., Manzanillo, P. S. & Cox, J. S. Cell 150, 803–815 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Castillo, E. F. et al. Proc. Natl Acad. Sci. USA 109, E3168–E3176 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Kimmey, J. M. et al. Nature 528, 565–569 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Golovkine, G. R. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-023-01354-6 (2023).

  6. Aylan, B. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-023-01335-9 (2023).

    Article  PubMed  Google Scholar 

  7. Deretic, V. & Lazarou, M. J. Cell. Biol. 221, e202203083 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Behar, S. M. & Baehrecke, E. H. Nature 528, 482–483 (2015).

    Article  CAS  PubMed  Google Scholar 

  9. Wang, F. et al. Developmental Cell https://doi.org/10.1016/j.devcel.2023.03.014 (2023).

    Article  PubMed  Google Scholar 

  10. Köster, S. et al. Proc. Natl Acad. Sci. USA 114, E8711–E8720 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Autophagy, Inflammation and Metabolism Center, University of New Mexico School of Medicine, Albuquerque, NM, USA

    Vojo Deretic & Fulong Wang

  2. Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, USA

    Vojo Deretic & Fulong Wang

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  1. Vojo Deretic
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  2. Fulong Wang
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Correspondence to Vojo Deretic.

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Deretic, V., Wang, F. Autophagy is part of the answer to tuberculosis. Nat Microbiol 8, 762–763 (2023). https://doi.org/10.1038/s41564-023-01373-3

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