Extended Data Fig. 10: Presence of irdA predicts itaconate reductase activity of E. lenta strains.
From: Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration
(a) Schematic diagram of itaconate reduction by IrdA, and sequence identity of the reductase with greatest similarity to IrdA is shown for indicated E. lenta strains strain. (b) Extracted ion chromatograms of authentic standard-matched methylsuccinate peaks from media collected after cultivation with the indicated strain.
