Extended Data Fig. 3: S. wadsworthensis growth-stimulating electron acceptors.
From: Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration
S. wadsworthensis growth in formate-supplemented media provisioned with electron acceptors: (a) labeled C4-dicarboxylates, (b) shikimate, (c) dimethyl sulfoxide, and (d) methionine sulfoxide. A ‘no electron acceptor’ condition and conditions with predicted products are included as controls. Extracted ion chromatograms of peaks (matched to available authentic standards) in uninoculated and inoculated growth media. (A) Fumarate and its succinate reduction were measured by LC-MS, the rest of (A) and (D) were measured by GC-MS; (B) was measured by LC-MS; support for identification of hydro-shikimate in (B) is provided in Supplementary Fig. 5. Data are mean ±SD (n = 3 independent biological replicates). *p < 0.05, **p < 0.01, *** p < 0.001. Two-way ANOVA, multiple test vs media alone.
