Extended Data Fig. 2: Volcano plots highlighting gut metabolite abundance changes between colonized and microbiota-free (MF) bees with and without pollen.
From: Host-derived organic acids enable gut colonization of the honey bee symbiont Snodgrassella alvi

Significantly differentially abundant metabolites between mono- and cocolonized S. alvi and Gilliamella vs MF bees, as well as between MF (Pollen +) versus MF (Pollen -) bees (bottom left). Significantly depleted and produced metabolites are shown in blue and orange, respectively. Annotations are listed in order of significance for identified metabolites, with isomers and other duplications removed. The full set of significantly more abundant metabolites in the first panel can be found in the supporting code. Adjusted significance values were calculated using a two-sided Wilcoxon rank sum test with BH correction, ((pollen ±): MF: n = 12/10; S. alvi: n = 11/12; S. alvi + Gilliamella: n = 13/14; Gilliamella: n = 10/13).