Fig. 4: Association of HLA variation with Lassa fever susceptibility. | Nature Microbiology

Fig. 4: Association of HLA variation with Lassa fever susceptibility.

From: Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever

Fig. 4

a, Imputation accuracy of four-digit HLA calls compared to sequencing-based ground truth sets from our Sierra Leone cohort, as well as Esan and Mende individuals from 1000 Genomes. b, Table of HLA alleles with the strongest association with Lassa fever susceptibility, ordered by meta-analysis of the NG and SL cohorts. P values are based on SAIGE, while meta-analysis P values are derived from meta-analysis (METAL) of P values generated from each cohort. ORs are computed from Firth logistic regression.

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