Extended Data Fig. 9: Evaluating the effect of diet on the defined community in gnotobiotic dam-pup dyads. | Nature Microbiology

Extended Data Fig. 9: Evaluating the effect of diet on the defined community in gnotobiotic dam-pup dyads.

From: Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition

Extended Data Fig. 9

(a) Experimental design (n = 2 dams and 12 offspring/diet treatment). (b) Principal component analysis showing the significant differences in community structure in the cecums of mice euthanized on P53 (P = 1x10-5; PERMANOVA). Ellipses represent 95% confidence intervals. (c) Absolute abundances of the defined community members in cecal contents at P53. Exact P-values for B. breve, B. catenulatum, B. infantis Bg2D9, D. formicigenerans, E. coli, F. prausnitzii, L. garavieae, L. ruminis, and M. multacida are 4×10-5, 4×10-5, 4×10-5, 6×10-4, 4×10-5, 2×10-4, 4×10-5, 1×10-4, and 4×10-5, respectively. P-values were calculated by PERMANOVA (panel b) and a two-sided Mann-Whitney U test (panel c). N.S., P-value > 0.05. Mean values ± SD are shown. Each dot represents an individual animal.

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