Fig. 6: EVs specifically inhibit viral pathogens depending on apoptotic mimicry.
a, Antiviral activity of semen EVs and PS (6.25 mol%)- and PC-liposomes tested against known viral apoptotic mimicry viruses ZIKV, DENV, WNV, CHIKV (all n = 3 biological replicates), EBOV(-trVLPs) (n = 3 independent experiments with mean biological triplicates each) or VSV (n = 2 independent experiments with mean biological triplicates each). b, Antiviral activity of semen EVs and PS- and PC-liposomes tested against viruses with known non-lipid receptors: SARS-CoV-2 (n = 2 independent experiments with biological triplicates each), HIV-1 (n = 3 biological replicates), HSV-1, HSV-2, HCMV (n = 2 independent experiments with biological triplicates each) or HCV (n = 3 biological replicates). Shown are mean values ± standard error of the mean.
