Extended Data Fig. 2: Conservation of Spt16 SUMOylation among eukaryotes.
From: FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins
a-c, IB of endogenous Spt16 proteins from indicated human (a) and mammalian animal cell lines (b) and from invertebrate cell lines and animal tissues (C. elegans) (c) showing SUMOylated (upper bands) and non-SUMOylated (lower bands) Spt16 forms. Non-human cell lines derive from the following: BSC-40 (Chlorocebus sabaeus); BHK-21 (Mesocricetus auratus); L929 (Mus musculus); SIRC (Oryctolagus cuniculus); R06E (Rousettus aegyptiacus); and LD652 (Lymantria dispar). Images in a-c are representative of at least two independent experiments.
