Extended Data Fig. 7: Phenotyping of T cell subsets in pre-vaccination diet switch cohorts.
From: Diet switch pre-vaccination improves immune response and metabolic status in formerly obese mice
Mean fluorescent intensity (MFI) of splenic CD98, MitoTracker Red (MTR CMXRos) and MitoTracker Green (MTG) in (a) CD4+ effector memory (TEFM) T cells, (b) CD4+ central memory (TCM) T cells, (c) CD8+ TEFM, and (d) CD8+ TCM cells. Data include mice with obesity, always lean, and mice that were formerly obese (n = 7, n = 7, n = 8 for each group, respectively) and graphed as boxplots with comparisons made between via one-way ANOVA with CD4+ TEFM MTG formerly obese p = 0.0148; and CD8+ TEFM cells MTR formerly obese p = 0.0172, MTG formerly obese p = 0.0034.
