Extended Data Fig. 6: Fibre mixture or pectin supplementation inhibits indole production and stimulates ILA production in complex human gut microbial communities in vitro.
(a) Concentrations of tryptophan metabolites in the individual culture supernatants of nine adult human faecal microbiota in mGAM medium supplemented either with pectin or with the mixture of fibres as described in methods. Results from one sample (S019) is missing for Tryptophan and ILA due to an error with the internal standard in the LC-MS for this sample. (b) 16S rRNA gene sequencing profiles show the composition of the microbiota community in each individual cultures.
