Extended Data Fig. 2: Relationship of index case self-reported ancestry and human-adapted M. tuberculosis complex lineage.
From: Differential rates of Mycobacterium tuberculosis transmission associate with host–pathogen sympatry
a) Bar plot detailing the proportions of isolation country and Mtbc lineage in a global sample of 25,243 strains. b) Adjusted odds ratios estimated for the variable contact allopatry using different co-localization or sympatry assumptions from multivariate Generalized Estimation Equation (GEE) models (see Fig. 3f in main text). No effect for L4widespread is shown. L2restricted includes sub-lineages 2.1., 2.2.2 and 2.2.1.1.2, L4restricted sub-lineages include 4.11, 4.2.1.1, 4.3.i2, 4.5, and 4.6.2.2. L2widespread refers to sub-lineages 2.2.1, 2.2.1.1, 2.2.1.1.1, 2.2.1.1.1i1, 2.2.1.1.1.i2, 2.2.1.1.1.i3, 2.2.1.2, L4 to all other L4 sub-lineages (see Methods). The bars represent the effect estimates from the GEE models with 95% confidence intervals. N = 2,556 contacts.
