Fig. 2: ‘Ca. E. childressi’ is a chemoorganoheterotroph that gains its nutrition from lipids, sugars and amino acids from its host. | Nature Microbiology

Fig. 2: ‘Ca. E. childressi’ is a chemoorganoheterotroph that gains its nutrition from lipids, sugars and amino acids from its host.

From: An intranuclear bacterial parasite of deep-sea mussels expresses apoptosis inhibitors acquired from its host

Fig. 2

Physiological reconstruction from bulk tissue transcriptomes and proteomes. ‘Ca. E. childressi’ transcriptomic expression is shown in circled genes, as TPMs normalized to recA TPMs, for levels from not detected (black) through low (blue) to high (yellow) (colour legend on bottom left). The expression levels of proteins are shown as coloured ‘P’ symbols next to their corresponding gene, with yellow showing high abundance (first quartile), turquoise medium abundance (second quartile) and blue low abundance (third quartile). ACAD, acyl-CoA dehydrogenase; ATPα, ATP synthase alpha chain; chiA, chitinase; comEA, late competence protein ComEA DNA receptor; comEC, DNA internalization-related competence protein ComEC; comF, competence protein F homologue; CPS, carbamoyl-phosphate synthase large chain; CTPS, cytidine triphosphate synthase; FATP, long-chain fatty acid transport protein; GFAT, glucosamine-fructose-6-phosphate aminotransferase; GPAT, amidophosphoribosyltransferase; ipgD1–2, Shigella-like inositol phosphate phosphatases; LC-FACS, long-chain-fatty-acid-CoA ligase; lcrV, T3SS translocon protein LcrV; LIP, lipase; MSBP, methionine ABC transporter substrate-binding protein; nagA, N-acetylglucosamine-6-phosphate deacetylase; oppB, oligopeptide transport system permease protein OppB; oppC, oligopeptide transport system permease protein OppC; pilA, type IV pilin PilA; pilC, type IV fimbrial assembly protein PilC; pilQ, type IV pilus biogenesis protein PilQ; pilT, twitching motility protein PilT; potF, putrescine ABC transporter putrescine-binding protein PotF; potG, putrescine transport ATP-binding protein PotG; PTSG, glucose-specific component of PTS system; ptsN, nitrogen-regulatory protein of PTS system PtsN; PTSP, phosphoenolpyruvate-protein phosphotransferase of the PTS system; recJ, single-stranded-DNA-specific exonuclease RecJ; secA, protein export cytoplasm protein SecA ATPase RNA helicase; secE, preprotein translocase subunit SecE; secG, preprotein translocase subunit SecG; secY, preprotein translocase secY subunit; SERT, serine transporter; THIO, thioredoxin; TS, thymidylate synthase; yuiF, histidine permease YuiF; yopB, T3SS translocon protein YopB; yopD, T3SS translocon protein YopD; β, β-oxidation of fatty acids. For space reasons, only central aspects of ‘Ca. E. childressi’ metabolism and physiology are shown; the complete list of expressed genes in transcriptomic and proteomic analyses is available in Supplementary Tables 9 and 10. Signal peptide analyses of DNAses, RNAses and proteases are shown in Supplementary Table 11.

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