Extended Data Fig. 3: Rates of undirected and directed inter-genus LGT for HMP1-II metagenomes profiled by WAAFLE.
From: Profiling lateral gene transfer events in the human microbiome using WAAFLE
LGT rates normalized to total assembly size in 1000 s of genes, stratified by body site and correspondingly colored by body area. (a) All inter-genus LGT events were considered, regardless of whether the donor and recipient clades were known. (b) Only directed inter-genus LGT events were considered (that is, cases where the donor and recipient clade were clear from gene adjacency). Major body sites are labeled in bold type. (c) Total assembly sizes for the same set of samples; only genes resolved to at least the genus level were counted. Only the first sequenced visit from each unique HMP1-II participant is plotted. Each box displays the first and third quartiles, with a horizontal line indicating the median, while the whiskers extend to 1.5x the interquartile range below Q1 and above Q3 (the inner fence) outside of which outliers are plotted as individual data points.
