Extended Data Fig. 1: Sample distribution and mapping quality control.
From: Ecological dynamics of Enterobacteriaceae in the human gut microbiome across global populations
a, Distribution of age groups, health states and continents of the 12,238 gut metagenomic samples. b, Comparison of taxonomic profiles and abundances of three mock community samples in relation to their expected proportions, estimated using the read mapping filtering parameters used in this study. c, Detection limit of our metagenomic approach evaluated with 120 synthetic metagenomics consisting of the top 50 most prevalent gut species and one Enterobacteriaceae species at a defined abundance across three levels of sequencing depth. Horizontal dashed line represents the minimum relative abundance at which the five Enterobacteriaceae species tested were detected. Abundance values are log-scaled. d, Two-sided Pearson correlation between the number of samples with or without Enterobacteriaceae across the 65 studies. Error band represents the 95% confidence interval.
