Extended Data Fig. 5: Supplement to Fig. 3.
From: Influenza A virus rapidly adapts particle shape to environmental pressures
a. Virion yields for MOI 10 (solid) and MOI 0.3 (open circle) infections of Calu3 cells with PR8 at various baloxavir concentrations. Red box indicates region of overlapping yields. b. Shape of virions from the shaded region in a. Dashed line: untreated. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 by two-tailed unpaired t-test relative to an untreated control. c. As in a except for Calu3 cells infected with XUdorn. d. As in b, except for Calu3 cells infected with XUdorn. In a and c, raw data for independent replicates is shown instead of averages to facilitate selection of individual data points within the highlighter yield regimes. All error bars show S.E.M. a-d. Data plotted derive from 3 biological replicates.
