Extended Data Fig. 4: ARF4 deletion interrupts ZIKV prM cleavage.
From: ARF4-mediated intracellular transport as a broad-spectrum antiviral target
a) Vero WT and ARF4−/− cells were infected by ZIKV at an MOI of 10. CL were collected at indicated timepoints post infection to performed WB using antibodies against both prM and cleaved M proteins. GAPDH here is used as loading control. b) The percentage of M to total expressing (prM+M) was calculated as an index of ZIKV prM cleavage. Data are representative of at least three independent experiments and shown as mean ± SD. The p-value were determined versus ZIKV infected samples by two-way ANOVA with multiple comparisons.
