Fig. 2: P. faecium DSM 32890 curbs body weight gain and adiposity, and restores glucose homeostasis in diet-induced obesity. | Nature Microbiology

Fig. 2: P. faecium DSM 32890 curbs body weight gain and adiposity, and restores glucose homeostasis in diet-induced obesity.

From: Gut commensal Phascolarctobacterium faecium retunes innate immunity to mitigate obesity and metabolic disease in mice

Fig. 2

a–f, Body weight evolution (a), body weight gain (b), weight of eWAT (c), plasma triglyceride levels (d), blood glucose levels after an oral glucose load (2 g kg−1) (e) and area under the curve (AUC) at week 10 of intervention (f). g–j, Fasting glucose (g), insulin (h), leptin (i) and GIP (j) levels in plasma. Control and HFHSD n = 10, HFHSD + P. faecium n = 9. Values are presented as mean ± s.e.m. of n biological replicates shown as individual dots. Significant differences were assessed using one- or two-way ANOVA followed by a post hoc Tukey’s test; *P < 0.05. In e, ‘*’ is used when compared to control diet and ‘#’ when compared to HFHSD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 and #P < 0.05.

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