Extended Data Fig. 1: Meta-analysis of association of Phascolarctobacterium species with BMI in a large-scale human cohort.

(a) Forest plot of a random effect meta-analysis of the presence of the species P. succinatutens (3,938 normal-weighted participants and 2,565 overweight). (b) Forest plot of a random effect meta-analysis of the presence of the species of Phascolarctobacterium spp. ET69 (3,486 normal-weighted participants and 2,088 overweight). Study name, sample sizes, and nationalities are reported. The overall logistic regression meta-analysis significance was assessed through two-tailed standard t-test against the null-hypothesis of a zero effect-size. Binomial tests assess the overproportion of single-datasets tests leaning toward one side of the plot assuming an expected proportion of 50%. Values are presented as mean ± 95% confidence intervals.