Extended Data Fig. 6: PflC forms oligomers in vitro regulated by its C-terminal PDZ domain.

(a) Size Exclusion Chromatography of PflC (red) along with protein standards (grey) showing elution volume. (b) Calibration graph showing a dimer of PflC (red) corresponding to retention times during elution. (c) Mass photometry measurements of purified PflC (replicates). (d) Size Exclusion Chromatography of PflCN (∆236–349, green) along with protein standards (grey) showing elution volume. (e) Calibration graph of PflCN (green) corresponding to retention times during elution. (f) Mass photometry measurements of purified PflCN. Theoretical masses are shown in the inserts. The instrument’s limit of detection is 35 kDA, meaning the monomer mass is larger than expected.