Extended Data Fig. 7: Structural comparison of Bab and related Bell bacterial proteins.
From: Characterization of an amyloid-based antiphage defence system in Escherichia coli
The experimental Bab structure and predicted AlphaFold3 structures of the Bell domain belonging to different clusters (as given in Supplementary Fig. 1) are presented with a rainbow coloring with blue to red from N- to C-terminus. The predicted pore-lining helix (as predicted with MEMSAT-SVM) is given in beige in each case. Bell1, 2 and 3 are from Streptomyces species (Actinobacteria) while the three Bell domains on the left, associated to the BASS4, 5 and 9 motifs are from Cyanobacteria (Supplementary Fig. 1). The lower model is obtained by rotating the upper model by 90° around a horizontal axis as marked.
