Fig. 4: Biodistribution of nanodecoys after inhalation.
a, Schematic showing study design of nanodecoy inhalation in CD1 mice. Created with BioRender.com. b, Corresponding quantitative results from c of DiD-labelled nanodecoys in heart, lung, liver, kidney and spleen tissues. Data are shown as mean ± SD, n = 3 animals. At least three images were taken. c, Representative confocal images of DiD-labelled nanodecoys (red) in tissue sections. d, Representative confocal images showing nanodecoys in lung tissues co-localizing with lung cells (AQP5, SFTPC) and macrophages (CD68) 24 h post-inhalation. Five images were taken. e, Quantification of the percentage of nanodecoy-positive macrophages (CD68). Data are shown as mean ± SD, n = 3 animals. Scale bar in c and d, 200 μm.
