Extended Data Fig. 2: GV-seeded cavitation at 3 MHz requires higher pressure levels.
From: Acoustically triggered mechanotherapy using genetically encoded gas vesicles
(a) Broadband signals recorded from GVs (0.3 nM) and BSA (matched in mg/mL to GVs concentration) insonated at 3 MHz. Broadband signal increased with pressure and was significantly higher for GV samples at PNP≥0.5 MPa (p < 0.05 for PNP < 1.33 MPa, and p < 0.001 at higher pressure levels, n = 8 independent samples). (b) Comparison between broadband signals from GVs insonated with 670 kHz and 3 MHz pulses (n = 16 and n = 8 independent samples, respectively). Error bars, mean ± s.e.m (a-b).
