Extended Data Fig. 3: High frame rate optical imaging of GV collapse and bubble cavitation.
From: Acoustically triggered mechanotherapy using genetically encoded gas vesicles
High-speed camera frames (left to right then top to bottom) of GV collapse and cavitation (200 ns between each frame, 31×31 μm field of view), focusing on a single bubble. Initial black spots, which correspond to intact GVs, first disappear due to collapse, liberating gas that coalesces into a cavitating bubble in this region. GVs were insonated with a single 30-cycle pulse with PNP of 1.4 MPa and a central frequency of 670 kHz.
