Extended Data Fig. 5: Group-level analyses of two-photon calcium imaging in rhesus macaque slice. | Nature Nanotechnology

Extended Data Fig. 5: Group-level analyses of two-photon calcium imaging in rhesus macaque slice.

From: Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain

Extended Data Fig. 5

a, Mean peak ΔF/F0 evoked by cells from hippocampus, thalamus, motor cortex, and orbitofrontal cortex after applying different numbers of pulses. b, Mean rise time of GCaMP8s responses in the four brain regions. Rise time is defined as time taken for the response to rise from 10% to 90% of the peak of the amplitude. c, Mean decay time constant of GCaMP8s responses in the four brain regions. Decay time constant was obtained by fitting sums of exponentials to the decay phase of the traces. d, Mean full width at half maximum (FWHM) of GCaMP8s responses in the four brain regions. e, Mean signal-to-noise ratio (SNR) of GCaMP8s responses in the four brain regions. SNR is defined as the peak amplitude divided by the standard deviation of the fluorescence signal before the electrical stimulation. Hippocampus: n = 3 cells. Thalamus: n = 2 cells. Motor cortex: n = 5 cells. Orbitofrontal cortex: n = 2 cells. Data is plotted as mean ± s.e.m.

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