Fig. 5: Cell cytotoxicity is controlled by acidic conditions.
From: A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns
a, Cell viability assay on SK-BR-3 cancer cells after treatment with PEG_pH_O6p origami at pH 7.4 or 6.5. b,c, Cancer cell apoptosis assay of DNA origami treatment at pH 7.4 or 6.5, measured by flow cytometry (Q1, necrotic cells; Q2, late apoptotic cells; Q3, early apoptotic cells; Q4, live cells). d–g, Cell viability assay at pH 7.4 of breast cancer cells (d) and human non-cancer cells, including T lymphocytes (e), kidney cells (f) and endothelial cells (g). n = 3 independent experiments. Data are presented as mean ± s.d.
