Extended Data Fig. 2: Radio-thin layer chromatography (radio-TLC) of aNP-89Zr-siRNA. | Nature Nanotechnology

Extended Data Fig. 2: Radio-thin layer chromatography (radio-TLC) of aNP-89Zr-siRNA.

From: Nature-inspired platform nanotechnology for RNA delivery to myeloid cells and their bone marrow progenitors

Extended Data Fig. 2

a. MALDI spectra indicating conjugation of DFO to the siRNA sense strand b. Radio-TLC analysis of free 89Zr (top left) showing a peak at 15 mm. The peak shifts when 89Zr is chelated to DFO-siRNA to yield 89Zr-siRNA (top right). 89Zr-siRNA was used for formulation of the prototype aNP (bottom right) and a control LNP (bottom left).

Back to article page