Extended Data Fig. 2: MW-TMPs facilitate ICD in vitro, related to Fig. 3. | Nature Nanotechnology

Extended Data Fig. 2: MW-TMPs facilitate ICD in vitro, related to Fig. 3.

From: Tumour-derived microparticles obtained through microwave irradiation induce immunogenic cell death in lung adenocarcinoma

Extended Data Fig. 2

(a) Representative FCM plots of apoptotic analysis for LLC cells treated with MW-TMPs or UV-TMPs by FCM analysis (n = 3). b) FCM analysis of HMGB1 expression in UV-TMPs and MW-TMPs (n = 3). (c, d) Representative FCM plots and quantitative analysis of CD86+ BMDCs (c) and T cell distribution (d) following co-culture of BMDCs and T cells with LLC cells pretreated with either UV-TMP or MW-TMP (n = 3). (e, f) Production of IFN-γ in the co-incubation system (e) or in the presence of the HMGB1 inhibitor (f) (n = 3). The data in (b and c-f) are shown in analytic plots as mean ± s.d. The t test (with two sides) was performed for the two independent groups in (b), and one-way ANOVA was used to test statistical significance among three or more groups in (c-f). The exact p value was noted.

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