Extended Data Fig. 7: Overlaid nanopore current traces and two-dimensional current intensity plots from the first 100 linear events recorded for E. coli (with m5C modification at the target site, a) and A. baumannii (without modification, b) carriers, both measured with their shared nanolatch design.

The orange circle refers to the latched loop formed on the E. coli carrier using the EAH nanolatch. Two methylated cytosines are present in the target RNA region. The yellow circle refers to the latched loop formed on the A. baumannii carrier using the same nanolatch. Only one methylated cytosine is present in the target RNA region.