Extended Data Fig. 9: Analysis of the Cell Cycle Timer differential growth model parameter space. | Nature Physics

Extended Data Fig. 9: Analysis of the Cell Cycle Timer differential growth model parameter space.

From: Clonal dominance in excitable cell networks

Extended Data Fig. 9

Final largest cluster size as fraction of total cell number at different \(\sigma _{{{\mathrm{f}}}}\) and \(\sigma _{{{\mathrm{s}}}}\), for \(t_{{{\mathrm{s}}}}\) = 9.6 h, averaged over 2,200 simulation runs, as a function of the mean division time ration between the fast and slow cell populations, \(t_{{{\mathrm{f}}}}/t_{{{\mathrm{s}}}}\), and the probability of each starting cluster being assigned to the fast population, \(p_{{{\mathrm{f}}}}\). Cyan-bordered region indicates where experimental and theoretical values are less than an experimental standard deviation apart (experimental value average over all chambers with >600 cells: largest cluster size fraction = 0.36, s.d. = 0.06, n = 7; Supplementary Table 3).

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