Fig. 2: Accelerator readiness and beam delivery stability.
From: Tumour irradiation in mice with a laser-accelerated proton beam
a, Daily LPA-source performance over a two-year period demonstrated via the highest recorded proton cut-off energy Ep,max from the Thomson parabola spectrometer (TPS, bars) and RCF stack (diamonds); the horizontal line at Ep,max = 60 MeV acts as a guide for the eye. The green bars correspond to the data in b and the blue bar, the data in c. Small animal irradiation days are highlighted by the dashed bars. b, Daily average of the dose delivery parameters (mean dose per shot \({\bar{D}}_{{{{\rm{shot}}}}}\) with 2σ standard deviation, mean depth \({{\Delta }}{\bar{H}}_{{{{\rm{depth}}}}}\) and lateral dose inhomogeneity \({{\Delta }}{\bar{H}}_{{{{\rm{lat}}}}}\)) and targeted parameter ranges (grey). The blue data points correspond to the data in c. c, Verification of the stability of all (consecutive) shots during a representative day of mouse irradiation measured by the transported kinetic-energy spectrum Ekin with Np,norm as normalized proton number, relative mean bunch energy fluctuation ΔEmean and dose delivery parameters (dose per shot Dshot and depth–dose inhomogeneity per shot ΔHdepth), all lying within the targeted parameter ranges (grey).
