Extended Data Fig. 3: Cell area of neural progenitors at cell division.
From: Cell cycle dynamics control fluidity of the developing mouse neuroepithelium
A. Snapshots from confocal time lapse imaging (Supplementary Video 5) of neuroepithelial cells expressing membrane GFP at E10.5. The first subapical z-section (shown) was used for tracing and quantification. Asterisk marks a dividing cell and its daughters. Scale bars, 5 μm. B. Mean cell area over time quantified from time-lapse movies such as the one shown in A. n = 17 cells from 3 embryos, shaded regions 95% confidence intervals. Time = 0 is the first time point where two distinct daughter cells were detected. Dividing cells rapidly increase their apical area prior to mitosis.
