Extended Data Fig. 6: The emergence of a laning pattern is independent from cell contractility.
From: Emergence of bidirectional cell laning from collective contact guidance
A laning pattern develops even when cell contractility is impaired by inhibiting myosin II with blebbistatin. The double arrow shows the direction of the grooves. Myosin II inhibition does not prevent collective cell guidance by the grooves and does not impair the emergence of a laning pattern. t = 20 h post-confluence, groove depth=1.45 μm.
