Extended Data Fig. 9: The groove depth is a good proxy of the friction anisotropy.
From: Emergence of bidirectional cell laning from collective contact guidance
a: vrms. as a function of groove depth. vrms. is practically independent from the substrate topography. Data are presented as mean values ± SD. See Methods section for n values. b: Antiparallel laning emerges when grooves are sufficiently deep. The bivariate histograms of (vx, vy). corresponding to these patterns evolve from a ring to a bimodal distribution of vx with very small fluctuations of vy (data from all the analyzed FOVs, n = 54, N = 32 (see table in Methods section)) are concatenated in these histograms). See Extended Data Fig. 8a for comparison with numerical simulations. c: Cumulative probability distribution function of lane width \(\tilde{p}(w)\) for different groove depths. See Extended Data Fig. 8c for comparison with numerical simulations. d: Evolution of the average lane width \(\bar{w}\) with the guidance order parameter S. \(\bar{w}\) is larger on deep grooves compared to flat or shallow substrates. See Extended Data Fig. 8d for comparison with numerical simulations. Data are presented as mean values ± SD. t = 20 h post-confluence.
