Extended Data Fig. 4: Dynamics of apparition of a laning pattern.
From: Emergence of bidirectional cell laning from collective contact guidance
a: Time evolution of vx in a HBEC monolayer on flat and on grooved substrates. The double-headed arrow indicates the groove orientation. Note that the system progressively jams with time. When normalized by vrms (bottom row), the laning pattern coarsens more and more slowly until t = 45 h and is lost only at long timescales when the system freezes and velocities approach 0. b: The time evolutions of the rms velocities are comparable on grooved (blue line) and flat (black line) substrates and the systems jam similarly in both cases. See also Extended Data Fig. 9a. Lines are mean values, coloured areas are standard deviations of the mean values distribution (n = 10 (resp. 7) on a flat (resp. grooved) substrate). d = 1.75 μm for the grooved substrates. All panels: t = 0 corresponds to confluence.
