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Tissue mechanics

Marangoni flows underlie symmetry breaking in early mouse gastruloids

Spherical aggregates of mouse stem cells exhibit symmetry breaking by forming an elongated axis. This extension is driven by a recirculating Marangoni-like tissue flow, providing insights into the tissue mechanics underlying embryonic development.

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Fig. 1: Rotational symmetry breaking and primary axis establishment in mouse gastruloids.

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Correspondence to Akanksha Jain.

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Jain, A. Marangoni flows underlie symmetry breaking in early mouse gastruloids. Nat. Phys. 21, 510–511 (2025). https://doi.org/10.1038/s41567-025-02840-w

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