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  • Review Article
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Environmental sustainability in cardiovascular practice: current challenges and future directions

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Abstract

Cardiovascular disease is the leading cause of morbidity and mortality worldwide, with a substantial amount of health-care resources targeted towards its diagnosis and management. Environmental sustainability in cardiovascular care can have an important role in reducing greenhouse gas emissions and pollution and could be beneficial for improving health metrics and societal well-being and minimizing the cost of health care. In this Review, we discuss the motivations and frameworks for sustainable cardiovascular care with an emphasis on the reduction of the climate-related and environmental effects of cardiovascular care. We also provide an overview of greenhouse gas emissions related to the provision of health care, including their measurement and quantification, carbon accounting, carbon disclosures and climate effects. The principles of life-cycle assessment, waste prevention and circular economics in health care are discussed, and the emissions associated with various sectors of cardiovascular care as well as the rationale for prevention as a powerful approach to reduce these emissions are presented. Finally, we highlight the challenges in environmental sustainability and future directions as applicable to cardiovascular practice.

Key points

  • Cardiovascular health and environmental health are interlinked; sustainable cardiovascular care is crucial for reducing emissions and pollution while improving outcomes.

  • Cardiovascular care has a large environmental footprint owing to high energy use and waste from devices and procedures; this footprint needs further quantification.

  • Strategies such as energy efficiency, renewable energy, waste reduction, disease prevention, innovation and circular economy principles can reduce carbon emissions and costs.

  • Lack of transparency and regulatory levers hampers current sustainability efforts, but frameworks for disclosures, target setting and reporting emissions are emerging.

  • Health-care leaders should measure emissions, set reduction targets, redesign care and engage stakeholders to transition towards sustainable models that improve value, outcomes and planetary health.

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Fig. 1: Measuring greenhouse gas emissions and the carbon footprint of health care.
Fig. 2: Life-cycle assessment framework.
Fig. 3: Butterfly representation of the circular economy principle adapted for health care.

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Change history

  • 16 May 2025

    In the version of the article initially published, the Acknowledgements section was missing and has now been added to the HTML and PDF versions of the article.

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Acknowledgements

Work in the laboratory of A.B. was supported in part by NIH Grant #P42 ES023716.

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S.R. and S.A.-K. researched data for the article. S.R., S.M., R.D.P., R.D.B., K.N., M.J.N., P.L. and S.A.-K. substantially contributed to the discussion of content. S.R. and S.A.-K. wrote the article. All authors reviewed/edited the manuscript before submission.

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Correspondence to Sanjay Rajagopalan or Sadeer Al-Kindi.

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C.V.S. is a salaried employee of Mazzetti. J.R.C. is a salaried employee of Eaton Corporation. K.H.B. is a salaried employee of the American Society for Health Care Engineering of the American Hospital Association. The views represented here are solely those of the authors and do not necessarily reflect the views of the authors’ employers. The other authors declare no competing interests.

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Rajagopalan, S., McAlister, S., Jay, J. et al. Environmental sustainability in cardiovascular practice: current challenges and future directions. Nat Rev Cardiol 22, 241–254 (2025). https://doi.org/10.1038/s41569-024-01077-z

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