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OpenEP and EP Workbench for electrophysiology data analysis

Nature Reviews Cardiology volume 22, page 3 (2025)Cite this article

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During electrophysiology procedures, acquired electroanatomic mapping data can provide insights into cardiac structure and electrical activity. The integration of electrical data (including cardiac conduction, voltage and electrogram data) into intra-procedurally created 3D anatomical maps can provide clinicians with a comprehensive insight into the anatomical and electrical properties responsible for the initiation and maintenance of arrhythmias.

Unfortunately, the utility of electroanatomic mapping data has been limited by the proprietary nature and storage-space inefficiency of electroanatomic mapping data. This is reflected in the lower volume of research outputs utilizing electroanatomic mapping data compared with data from other cardiology modalities, such as electrocardiography and cardiac imaging data. The development of a standardized approach for electroanatomic mapping data collection, transfer and analysis could, therefore, improve the utility of such data for research.

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Acknowledgements

The authors acknowledge the members of the University of Edinburgh–King’s College London Arrhythmia and Electrophysiology research group for their ongoing work to develop the OpenEP framework.

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  1. King’s College London, London, UK

    Neil Bodagh

  2. University of Edinburgh, Edinburgh, UK

    Steven E. Williams

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  1. Neil Bodagh
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  2. Steven E. Williams
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Correspondence to Neil Bodagh.

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The University Court of The University of Edinburgh has filed a patent application (application number 2414394.3, filed on 1 October 2024) related to aspects of this manuscript. The list of inventors will be finalized before Patent Cooperation Treaty filing. The specific aspect of the manuscript covered by this patent application is the description of the ReCETT-AF study, which is discussed in the penultimate paragraph of the manuscript. The patent application is currently pending.

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Bodagh, N., Williams, S.E. OpenEP and EP Workbench for electrophysiology data analysis. Nat Rev Cardiol 22, 3 (2025). https://doi.org/10.1038/s41569-024-01092-0

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