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Value-based pricing of drugs with multiple indications or in combinations — lessons from Europe

Nature Reviews Clinical Oncology volume 19, pages 1–2 (2022)Cite this article

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Legislators in the USA have been discussing reforms to reduce the high cost of brand-name drugs, which are much higher in the USA than in other industrialized countries. One solution is to actively negotiate prices based on drugs’ clinical benefits. We discuss two important complexities from such an approach: drugs that have been approved for multiple indications and as part of a combination regimen.

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Acknowledgements

The authors are grateful to David L. Carl (University of Zurich) for assistance with a previous version of the manuscript. The work of K.N.V. is partially funded by the Swiss National Science Foundation (SNSF). The work of A.S.K. is supported by Arnold Ventures.

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Authors and Affiliations

  1. Institute of Law, University of Zurich, Zurich, Switzerland

    Kerstin N. Vokinger

  2. Program on Regulation, Therapeutics, and Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

    Kerstin N. Vokinger & Aaron S. Kesselheim

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  1. Kerstin N. Vokinger
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  2. Aaron S. Kesselheim
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Correspondence to Kerstin N. Vokinger.

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Vokinger, K.N., Kesselheim, A.S. Value-based pricing of drugs with multiple indications or in combinations — lessons from Europe. Nat Rev Clin Oncol 19, 1–2 (2022). https://doi.org/10.1038/s41571-021-00561-6

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